How is your intake with water and your nutrition with vegetables and less red meat?
Please go through his/her research paper and ask him/her questions, provide your comments. The key to keeping us looking young, scientists found might be telomeres. Interested in learning about the significance of telomeres, I will go over the research history, the importance of
telomeres relating to the aging process. Lastly, what we can do, if anything, to accommodate telomeres in the aging process. Telomeres are
DNA-protein complexes that bend and fold repeatedly to form caps at the ends of chromosomes. This incredible enzyme holds valuable information as to how we age and why individuals get diseases, like cancer. Telomeres play a central role in cell fate and aging by, “adjusting the cellular response to stress and growth stimulation on the basis of previous cell divisions and DNA damage. According to the National Institute of
Medicine, “At least a few hundred nucleotides of telomere repeats must “cap” each chromosome end to avoid activation of DNA repair pathways. There are indications that in humans, the number of cell divisions that a cell and its descendants undergo is regulated at the chromosome level by structures called telomeres. These are unique DNA sequencing found at the end of our chromosomes.” If we had enough telomeres in our cells, our telomeres might not shorten at all. The concept of telomere was born in the 1930’s, McClintock and Muller found the existence of a
unique structure at the ends of chromosomes. They hypothesized that it was critical for prevention of chromosome end fusion. Muller coined the term “telomere” from the Greek telos, meaning “end,” and meros, meaning “part”; hence, “end part.” Over the years when scientists began to understand how genes are copied, by the 1950’s DNA strands base by base, to form the genetic code, are copied and DNA polymerase enzymes are present, but learned at the end of chromosomes could not be copied. After a couple decades of research in her early research career, Elizabeth Blackburn mapped DNA sequences. The same time Jack Szostak made a similar observation that a, “linear DNA molecule, a type of minichromosome, is rapidly degraded when introduced into yeast cells. In the 1980’s they presented the results from the DNA Tetrahymena, isolating CCCCAA sequence. Szostak and Blackburn published the results that telomere DNA with its characteristic sequence is present in most plants and animals from amoeba to man.” Presently, In 2009 Blackburn won a Nobel Prize in Physiology or Medicine, she was awarded for her telomerase research. Active telomerase can halt aging. Unfortunately, there is a catch within adult’s telomerase activation is a key step in the development of cancer. Many scientists and researchers have found that chronic stress in women and Psychological stress contributes to numerous diseases and in time can cause damage to telomeres, protective non-coding segments on the ends of chromosomes. Stressed, depressed, anxious, or previously traumatized individuals may have shorter telomeres than their psychologically healthy counterparts. In a recent study done in 2016 researchers mentioned, “stressor exposure within the last five years as well as chronic social stress are associated with shorter telomeres. Since the first study documenting a relationship between telomere length and perceived stress, many studies measuring telomere length have included a measure of psychological stress. Over the last decade with more research about telomeres, you can now have personalized blood testing for your DNA, pills to buy from big pharma or read anti-aging books that sell about staying younger relating
to telomeres. But, that does not always help the naturally way to help your telomeres. Scientists have reported the effects of perceived stress on telomere length.” During your daily health care routine, try and remember every day is an aging process, internally telomeres themselves, are
subject to wear and tear over the years in our adult life. When was the last time you made time for self care or a skin care routine? Do you get
enough sleep? How is your intake with water and your nutrition with vegetables and less red meat? Lastly, how is your stress and physical activity level? Concluding my research, we have learned the history and research of Telomeres. How telomeres shorten with age. Lastly, how we could naturally and positively increase our telomeres. As the research has shown physical activity, eating healthy; staying away from red meat and alcohol with less stress in life, can naturally increase our telomeres.